This paper offers an analysis of the primary wrong of epistemic injustice, namely, of the intrinsic harm that constitutes its action itself. Contrary to Miranda Fricker, I shall argue that there is...

The origin of chordates and the consequent genesis of vertebrates were major events in natural history. The amphioxus (lancelet) is now recognised as the closest extant relative to the stem chordate and is the only living invertebrate that retains a vertebrate‐like development and body plan through its lifespan, despite more than 500 million years of independent evolution from the stem vertebrate. The inspiring data coming from its recently sequenced genome confirms that amphioxus has a prototypical chordate genome with respect to (...) gene content and structure, and even chromosomal organisation. Pushed by joint efforts of amphioxus researchers, amphioxus is now entering a new era, namely its maturation as a laboratory model, through the availability of a large amount of molecular data and the advent of experimental manipulation of the embryo. These two facts may well serve to illuminate the hidden secrets of the genetic changes that generated, among other vertebrates, ourselves. (shrink)

I. On Philosophical Education To many philosophical sensibilities the expression “Pragmatic Naturalism” may sound like a sort of oxymoron. We have a good news: it is not. John Ryder’s new book The Things on Heaven and Earth will not persuade perhaps the most reluctant partisans of both sides, but it certainly shows how “pragmatic naturalism” is not necessarily a contradictio in adjecto, but rather an exciting theoretical approach. After reading this book, one acquires the confidence that prag...

Literature on epistemic injustice has grown tremendously as an increasingly rich and diverse body of work in recent years. From the point of view of intercultural and anticolonial discussions, contemporary contributions have also helped to illuminate how epistemic injustice and other forms of cultural domination might be related to essential processes within the structures of colonial and racial supremacy. -/- This proposal aims to contribute to such relevant and illuminating discussions by focusing on the role that language and culture might (...) have in phenomena of epistemic injustice, particularly, hermeneutical injustice. Despite the central role played by semantics in epistemic injustice studies, the question about whether certain languages could also themselves be the recipients of epistemic injustice has been rather undertheorized. Simultaneously, recent movements to advocate for minority language rights, such as the Linguistic Human Rights Movement (LHR), raise important questions in this connection. -/- In the present paper, I argue that attending to the intercultural context reveals a new sort of hermeneutical injustice, one that, surprisingly, has never been articulated before. In particular, I am referring to a kind of HI that is essentially “linguistic” and “culture-specific”. I will be presenting two different subtypes for this kind of hermeneutical injustice: The first concerns the possibility of considering certain languages themselves as genuine objects of hermeneutical injustice, while the second has to do with certain specific culturally-established expressions or forms of talking. (shrink)

Understanding how the chordate body plan originated and evolved is still controversial. The discovery by Spemann and Mangold in 1924 of the vertebrate organizer and its inductive properties in patterning the AP and DV axis was followed by a long gap until the 1960s when scientists started characterizing the molecular events responsible for such inductions. However, the evolutionary origin of the organizer itself remained obscure until very recently; did it appear together with the origin and radiation of vertebrates, or was (...) it a chordate affair? A recent study by Yu and collaborators,1 which analyses the expression of several organizer‐specific genes in amphioxus together with recent phylogenetic data that reversed the position of invertebrate extant chordates (e.g. urochordates and cephalochordates), indicates that the organizer probably appeared in early chordates. It likely had separate signalling centres generating BMP and Wnt signalling gradients along the DV and AP axis. The organizer was then lost in the urochordate lineage, most probably as an adaptation to a rapid and determinate development. BioEssays 29:619–624, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

La pandemia mundial del coronavirus ha supuesto una de las mayores conmociones de nuestra historia reciente y, como tal, parece obligarnos a repensar nuestros modos de organización y formas de vida e, incluso, como se propone aquí, a plantearnos cómo podríamos habitar el colapso. En este escenario incierto y desconocido, la filosofía, con sus múltiples enfoques y subdisciplinas, se presenta como un lugar privilegiado para analizar las vertiginosas transformaciones que han dado lugar a esta “nueva normalidad”. El presente monográfico aglutina (...) una serie de contribuciones realizadas por distintos investigadores e investigadoras de la Universidad de Oviedo, que han tratado de abordar la crisis sanitaria global desde diversas perspectivas filosóficas y humanísticas. Entre los temas que se estudian en estas páginas, figuran los relativos a la gestión de la pandemia y la comunicación científica sobre la misma, las relaciones entre pobreza, salud mental y suicidio o el alcance de la revalorización del mundo rural. También se utilizan las herramientas del análisis biopolítico para examinar la gestión de los cuerpos durante la pandemia a partir de tres ejes distintos: el tratamiento de los enfermos, los nuevos dispositivos de control y la gestión de la pandemia en las instituciones de encierro. Además, varios de los capítulos se ocupan explícitamente de un tema inherente a la mayoría de las reflexiones que componen este volumen: a saber, el de la necesidad de un cuestionamiento profundo de la sociedad occidental contemporánea y la insostenibilidad de su forma de vida. (shrink)

Alternative splicing (AS) is a widespread mechanism with an important role in increasing transcriptome and proteome diversity by generating multiple different products from the same gene. Evolutionary studies of AS have focused primarily on the conservation of alternatively spliced sequences or of the AS pattern of those sequences itself. Less is known about the evolution of the regulation of AS, but several studies, working from different perspectives, have recently made significant progress. Here, we categorize the different levels of AS evolution, (...) and summarize the studies on evolution of AS regulation, which point to a high level of evolutionary conservation of the regulation of AS events conserved between related species. This suggests that the quantitative regulation of AS is an intrinsic part of AS function. We discuss the potential role of changes in developmental regulation of AS as an additional layer in complex gene regulatory networks and in the emergence of genetic novelties. (shrink)

Open Education opens up learning opportunities to, potentially, every person in the world. Additionally, it allows teachers, researchers, and practitioners to find, share, reuse, and improve existing resources under a dependable legal framework. Aiming to spread and foster the introduction of open policies in Higher Education institutions, the gamified interactive learning experience Catch the Open! was developed. Catch the Open! targets HE educators who wish to learn, or who wish to deepen their existing knowledge, about OE and Open Educational Practices. (...) Within the gamified learning experience, the user becomes an educator, Alex, the game character, who receives a task from the Rector: to investigate how to best include OE and OEP in teaching and learning practice within the institution. Alex proceeds to explore and gather information in a web-based 2D virtual HE institution where students, colleagues, and guest researchers will help her to develop a comprehensive understanding of OE and the practical application of OEP. The educational content within Catch the Open! is underpinned by an OE competences framework for HE educators, developed in a previous phase of the Erasmus+ OpenGame project. In this paper, the design process to link pedagogical and technological approaches, which results in the Catch the Open! gamified web-based interactive application, is presented as well as the application itself. Moreover, two phases of piloting with 153 HE educators from six different HE institutions are presented. The obtained findings showed that the gamified environment helped in learning about OE. On the other hand, learners also suggested several improvement aspects of the gamified environment, such as the length of finishing a learning mission while playing. (shrink)

Attention-deficit hyperactivity disorder is one of the most common neurodevelopmental disorders in children and adolescents. People who have this disorder are characterized by presenting difficulties in the processes of sustained attention, being very active, and having poor control of their impulses. Despite the high prevalence of this disorder and the existence of various tests used for its diagnosis, few data are available regarding the usefulness and diagnostic validity of these tools. Given the difficulties that these subjects present in executive functions, (...) the aim of this study was to evaluate whether the Neuropsychological Assessment of Executive Functions battery for Children allows to establish specific profiles of executive performance for people with attention-deficit hyperactivity disorder. The sample was made up of 197 participants of both sexes, aged between 6 and 12 years age. A nonexperimental design was followed, using a comparative descriptive study method. The results indicated that the scales of phonological fluency, color path, rings, and interference are the most associated with the diagnosis of ADHD, providing data on inhibition, mental flexibility, sustained and selective attention, planning, verbal fluency, and working memory, among others. The practical implication of these results is in line with providing support in the clinical diagnosis that is carried out in children’s mental health units. In addition, the ENFEN tool can be valued as a suitable psychometric instrument in the psychoeducational field, helping professionals in a school environment to be more aware of the areas of cognitive development in which a student diagnosed with ADHD will have more difficulties and, in doing so, providing more adjusted and effective psychopedagogical measures when it comes to supporting students in their adaptation to the school environment. (shrink)

While rooted in careful study of Mead’s original writings and transcribed lectures and the historical context in which that work was carried out, the papers in this volume have brought Mead’s work to bear on contemporary issues in metaphysics, epistemology, cognitive science, and social and political philosophy.

Se expone el resultado de una investigación sobre algunos aspectos de la vida y obra del médico y patriota cubano Diego Tamayo Figueredo, con el objetivo de revelar hechos trascendentales que definen su vocación médica, humanista e independentista. Para su elaboración se realizó una revisión documental sobre esta personalidad histórica. Results about some aspects of Diego Tamayo Figueredo's life and work, Cuban physician and patriot, were exposed; with the objective of revealing transcendental facts that define his medical, humanist and independentist (...) vocation. To elaborate this work a documental review about this historical personality was made. (shrink)

La autora analiza algunas teorías filosóficas esenciales y muestra las diferencias entre los dos tipos actuales de constructivismo: la teoría foucaultiana y la teoría del feminismo de la igualdad, la cual forma parte del mensaje emancipador de la ilustración. Contraria a las teorías post-modernas de sujeto y genero, opta por continuar la investigación del genero y la sexualidad como construcciones políticas. Esta investigación seria la expresión teórica del movimiento feminista que lucha por la igualdad; y en consecuencia, este combate produciría (...) la disolución de los grupos de genero en una multiplicidad de individuos. (shrink)

En nuestra época asistimos a una auténtica proliferación de derechos. No hay conflicto ni problema humano que no desemboque en un debate acerca de los derechos que tenemos y cuya protección exigimos. Un panorama así estructurado da lugar a la irrupción de múltiples desafíos para una teoría de los derechoshumanos. Estos pueden ser tanto teóricos como prácticos. En este trabajo se señala un reto teórico peculiar: el de la necesidad de clarificar y determinar muy bien el alcance de cualquier ideología (...) política que contenga una teoría de los derechos humanos. Se ha elegido, en la actualidad, la teoría de lo Común con el fin de compararla con las consecuencias políticas de dos teorías que, de alguna manera, la han precedido históricamente: la voluntad general de J. J. Rousseauy la propuesta de un ser genérico elaborada por C. Marx. (shrink)

Aonio Paleario destacó por la defensa de posiciones filóginas que procurarían desmitificar las estructuras del patriarcado. Basado en el examen filológico de _Dell’economia o vero del governo della casa_ (1555), este artículo pone de manifiesto cómo Paleario consideraba a las mujeres del todo idóneas para la administración de bienes y recursos. Para el autor, ser hombre no se asocia necesariamente con dar una imagen de pulcritud y profesionalidad en la gestión del patrimonio familiar. Por ello, promoviendo acciones específicas en favor (...) de las mujeres, Paleario se sirve de su pensamiento discursivo para demostrar cómo la participación del colectivo femenino en la economía doméstica resulta clave para el desarrollo de la familia. (shrink)

The main purpose of this study was to analyze the presence and current situation of the game of skittles throughout the northern route of the Camino de Santiago. Thus, we considered its current practice, modalities, where it is played, and its different manifestations as an informal and formal game, comparing it with other traditional games on this pilgrimage route. To do this, a mixed qualitative-quantitative study was designed with 89 participants, constituting an informant for each municipality through which the Northern (...) Way passes. An ad hoc questionnaire was used for the data collection, which was processed through content analysis by expert judges and by using the IBM-SPSS statistical package. The results of the study show notable skittles activity on the Northern Camino, reflected in the number of skittles alleys, the number of clubs, associations, and peñas participating in federated leagues, and the wide range of varieties of skittles currently active on the Camino. The relationship between skittles and local culture, both symbols of identity in these northern Spanish regions, made it possible to preserve the traditional heritage in these places, keeping it alive today, despite the push toward new and more attractive leisure and sport trends. (shrink)

Inthe IV century b. C., in Grece, appears a theory that links, in a systematicalway, a series of events and discourses which outline the activity of the poets,musicians , dancers, sofistics, painters and sculptors, whose techne isexplained in relation with the imitation, understood as imitation of t..

Introduction: Congruence, understood as the agreement between the patient's preferred place of death and their actual place of death, is emerging as one of the main variables indicating the quality of end-of-life care. The aim of this research was to conduct a systematic literature review on levels and determinants of congruence in palliative patients over the period 2010–2021.Method: A systematic review of the literature in the databases of PubMed, Scopus, Web of Science, PsycINFO, CINAHL, Cuiden, the Cochrane Library, CSIC Indexes, (...) and IBECS. Information was extracted on research characteristics, congruence, and associated factors.Results: A total of 30 studies were identified, mainly of retrospective observational design. The congruence values varied substantially between the various studies, ranging from 21 to 100%. The main predictors of congruence include illness-related factors, individual factors, and environmental factors.Conclusion: This review, in comparison with previous studies, shows that treatment-related factors such as physical pain control, marital status, having a non-working relative, age, discussing preferred place of death with a healthcare professional, and caregiver's preference have been associated with higher levels of congruence. Depending on the study, other factors have been associated with either higher or lower congruence, such as the patient's diagnosis, gender, or place of residence. This information is useful for designing interventions aimed towards greater congruence at the end of life. (shrink)

Tras los graves acontecimientos sufridos en 2020 por la aparición del Covid y su consiguiente confinamiento, los centros educativos se vieron obligados a modificar sus metodologías tradicionales para llevar a cabo un adecuado proceso de enseñanza-aprendizaje.El objetivo principal de este estudio es conocer el grado de alfabetización digital de la comunidad educativa, es decir, si profesores, alumnos y padres de alumnos tienen las habilidades suficientes para ser competentes en el uso de las nuevas tecnologías adaptadas al entorno educativo.

This article studies Polo's interpretation of the relation that Leibniz establishes between possibility and necessity. The necessity, understood as the totality of the possibility, allows Leibniz to reach the final formulation of the ontologic argument to demonstrate the existence of God, as well as to describe the essence of the Absolute.

This article analyzes the construction of female subjectivity in the specific context of audiovisual cyberspaces in Spain dedicated to the struggle against violence against women. Looking at the YouTube channels of two virtual feminist communities that deal with violence against women, the authors analyze how the victim-subject is configured in terms of agency and activism. The authors adopt a multimodal model of studying the sign complexes of the videos as semiotic artifacts that produce meaning. Sign complexes are always engaged because (...) representation is never neutral because what is represented in sign is meant to realize the values and positions of those who make the sign. In this article, the authors understand feminist activism in the fight against violence targeting women as constructing in its discourse not only the activist process, but also the subject of this activism: the victim-subject of gender-based violence. The analysis engages in the discussion about the various ways in which this subject is interpellated by the audiovisual texts in terms of agency. As a result, this study proposes the necessity to devise new ways of articulating this subject as a political and agential one. (shrink)

El término estrés es una aportación de un médico húngaro llamado Has Selye (1907-1982). Su primera intuición sobre la existencia de este proceso psicológico se produjo mientras realizaba su rotatorio hospitalario al final de sus estudios de medicina. Observó que todos los pacientes, independientemente de la enfermedad que padecieran, presentaban unos síntomas comunes que denominó el síndrome de "simplemente estar enfermo", y que posteriormente en su tesis doctoral fue renombrado como "síndrome general de adaptación". Esto dio lugar a que el (...) resto de su vida lo dedicara al estudio y formalización del concepto de estrés. (shrink)

Se trata de una reflexión interdisciplinar, a partir de W. Benjamin, sobre las relaciones entre experiencia, tiempo y memoria histórica. La primera parte analiza el empobrecimiento moderno de la "erfahrung" que genera una "nueva barbarie", a la vez que experimentación innovadora, y que reclama un concepto más rico de experiencia, ligada a la totalidad concreta de la existencia. La segunda señala algunas paradojas de la memoria, muestra la inconsistencia del tiempo, cristalizado en el mito de "cronos", como principio ordenador, y (...) toma en consideración experiencias relevantes que requieren concebir otro tiempo. En esa dirección, la tercera parte desarrolla la idea de "jetztzeit", núcleo de la concepción crítica de la historia como tradición de los oprimidos, en cuyos instantes de peligro relampaguea el "angelus novus. (shrink)